Arthritis gout is a progressive chronic disease that occurs because of deposition of uric acid crystals in the tissue around the joint causing pain. One natural way to deal with pain and inflammation is by compressing using jelly which contains ginger essential oil. The objective of this research was to determine the effectiveness of red ginger jelly compress on the degree of pain and inflammatory status of patients of Arthritis gout in the work area of a health center in Ambon, Indonesia. The research design used in this study was quasi-experimental with a randomized control group pre-test and post-test design approach. The sample in this study was 36 people obtained from Stratified Random Sampling. The degree of pain was measured using the Numerical Rating Scale. The experiment was done by giving red ginger jelly compress with a dose of 4% for 20 minutes per day in 3 days. The paired t-test showed that the average difference in degrees of pain in pre-test and post-test of jelly ginger compress was 2.78 with a standard deviation of 0.548 and a p-value of 0.001. The average difference in inflammation status before and after the administration of red ginger jelly compress was 1.33 with a standard deviation of 0.594 and p-value of 0.00. Administration of red ginger jelly compress with a dose of 4% for 20 minutes per day in 3 days could reduce the degree of pain and inflammation status in Arthritis gout patients.